Setting higher standards means always thinking ahead

Anatrace® continues to be a leader in supplying high-purity detergents to research facilities, academic institutions, and industrial customers. Since the launch of our first detergent, Dodecyl Maltoside (DDM), our product offering of unique detergents has grown into the largest in the industry. We take pride in helping you unravel once unsolvable challenges by adding new items to our product portfolio. Please keep checking this page as we’ll be adding products as they become available. 


Mannitol-based Amphiphiles (MNA)

MNA detergents are a variation to the molecular architecture of the Neopentyl Glycol class of detergents. These detergents contain two flexible twelve carbon alkyl chains connected to four glucose groups via a mannitol linker. MNA-C12 will be available in July 2016, while MNA-C13 and MNA-C14 will be available in late Summer, 2016.  



 
Premixed Bicelles

In order to provide options for bicelle crystallization, Anatrace is excited to offer pre-mixed bicelle solutions of the two most commonly used lipid–detergent combinations. Anatrace pre-mixed bicelles are available as 250 µl of 30% stock solutions of either 2.8:1 DMPC:CHAPSO (D606:C317 BIC MIX 0.25 ML) or 2.8:1 DMPC:DHPC (D606:D514 BIC MIX 0.25 ML).



PreMixed Bicelles

MPA410 3-Decyloxypropyl-1- β-D-Maltopyranoside

MPA4 was originally created as a control detergent to test the effectiveness of the new neopentyl glycol detergents.  In these tests, this detergent showed promising results on a number of different membrane proteins which were comparable to DDM.  MPA4-C10 contains a 10-carbon alkyl making it comparable to the highly effective detergent Decyl Maltoside (DM).  Additionally, the CMC of MPA4-C10 is four times higher than DM, rendering it with potentially better extraction capabilities.



 

MPA412 3-Dodecyloxypropyl-1- β-D-Maltopyranoside

MPA4 was originally created as a control detergent to test the effectiveness of the new neopentyl glycol detergents.  In these tests, this detergent showed promising results on a number of different membrane proteins which were comparable to DDM.  MPA4-C12 contains a 12-carbon alkyl making it comparable to the highly effective detergent DDM.  Additionally, the CMC of MPA4-C12 is four times higher than DDM, rendering it with potentially better extraction capabilities.



 

NG300     Undecyl Maltose Neopentyl Glycol

The newest member of our family of neopentyl glycol detergents.  UMNG is the perfect intermediate molecule between the 12 carbon chain length of Lauryl-Maltose Neopentyl Glycol (LMNG) and the 10 carbon chain length of Decyl-Maltose Neopentyl Glycol (DMNG).



 

3DDTre     Lauryl-3-Trehaloside

Based on the molecular architecture of DDM, these new Trehalose detergents replace the head group maltoside with a trehalose disaccharide.  These detergents have demonstrated success in the solubilization and purification of a number of membrane proteins, and are the perfect detergent to try when DDM falls short.  3-DDTre links the 12 carbon alkyl chain to the third hydroxyl group of the trehalose disaccharide.  Each of the structural isomers of these trehaloside detergents show differences in molecular geometry, which has an effect on the properties of the detergents when compared to DDM.



 

4DDTre     Lauryl-4-Trehaloside

Based on the molecular architecture of DDM, these new Trehalose detergents replace the head group maltoside with a trehalose disaccharide.  These detergents have demonstrated success in the solubilization and purification of a number of membrane proteins, and are the perfect detergent to try when DDM falls short.  4-DDTre links the 12 carbon alkyl chain to the fourth hydroxyl group of the trehalose disaccharide.  Each of the structural isomers of these trehaloside detergents show differences in molecular geometry, which has an effect on the properties of the detergents when compared to DDM.


 

6DDTre     Lauryl-6-Trehaloside

Based on the molecular architecture of DDM, these new Trehalose detergents replace the head group maltoside with a trehalose disaccharide.  These detergents have demonstrated success in the solubilization and purification of a number of membrane proteins, and are the perfect detergent to try when DDM falls short.  6-DDTre links the 12 carbon alkyl chain to the sixth hydroxyl group of the trehalose disaccharide.  Each of the structural isomers of these trehaloside detergents show differences in molecular geometry, which has an effect on the properties of the detergents when compared to DDM.