D310-CH210 - 10:1 DDM/CHS Pre-Made Solution

● Formulation components – Dodecyl Maltoside (D310) and Cholesteryl Hemisuccinate (CH210)
● Formulation - 
               o  10:1 Dodecyl Maltoside to Cholesteryl Hemisuccinate (CH210) in deionized water               
               o   Final concentration 10% Dodecyl Maltoside (D310) to 1% Cholesteryl Hemisuccinate (CH210)
               o   Typical working concentrations: 1% DDM, 0.1% CHS for protein extraction and 0.1% DDM, 0.01%                                         CHS for protein purification.
● Appearance – Clear liquid
● Quality Assurance Tested – tested to 5 freeze thaw cycles



Below is a sample of structures solved with DDM/CHS⁽¹⁾:  

Protein	Family	Extraction Detergent	Purification Detergent	Gel Filtration Detergent	PDB ID (linked)
ZMPSTE24	Intramembrane protease	DDM + CHS	DDM + CHS	DDM + CHS	4AW6
N/OFQ receptor	GPCR	DDM + CHS	DDM + CHS	DDM + CHS	4EA3
CCR5	GPCR	DDM + CHS	DDM + CHS	DDM + CHS	4MBS
PAR1	GPCR	DDM + CHS	DDM + CHS	DDM + CHS	3VW7
5-HT1B/2B serotonin receptor	GPCR	DDM + CHS	DDM + CHS	DDM + CHS	4IAQ
Smoothened receptor	GPCR	DDM + CHS	DDM + CHS	DDM + CHS	4JKV
Glucagon receptor	GPCR	DDM + CHS	DDM + CHS	DDM + CHS	4L6R
Metabotropic glutamate receptor 1	GPCR	DDM + CHS	DDM + CHS	DDM + CHS	4OR2

Citation:
1. He, Y., Wang, K., and Yan, N. (2014) Protein Cell 5(9), 658-672.

No data available.

No data available.